Compression Guidelines for Diagnostic Telepathology
David Foran(1), Peter Meer(2,4), Thomas Papathomas(3), Ivan Marsic(4)
(1)BioImaging Laboratory, Department of Pathology and Laboratory Medicine
UMDNJ-Robert Wood Johnson Medical School
Piscataway, NJ 08855, USA
(2)Department of Electrical and Computer Engineering
(3)Department of Biomedical Engineering
(4)The Center For Computer Aids for Industrial Productivity
Rutgers University, Piscataway, NJ 08855, USA
As the healthcare community has begun to rely increasingly upon
digital technologies for acquisition, storage, and transmission of
pictorial data, image compression has become indispensable tool.
We have investigated the feasibility of lossy
compression in a well defined
task domain, the clinical assessment of digitized images of chromatic,
microscopic pathology specimens.
The effect of compression was measured under two distinct
perceptual criteria, just noticeable difference (j.n.d.) and largest
tolerable distortion (l.t.d.),
differing in the involvement required from subjects, who were experts
For standard JPEG compressed images
it was found that when the experiment is performed under the l.t.d.
criterion, a significantly larger compression ratio
is reported as satisfactory.
It is concluded that lossy compression of pathology images holds
promise for diagnostic telepathology.
IEEE Trans. on Information Technology in Biomedicine,
1 , 55- 60, March 1997.
A shorter version appeared in
1996 International Conference on Image Processing, Lausanne,
Switzerland, September 1996, vol.1, 873-877.